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June 28, 2025At Este Hair Medical, we pride ourselves on staying ahead of cutting-edge aesthetic treatments that not only enhance beauty but also restore the skin's natural vitality. One of the most exciting innovations in regenerative skincare is the polynucleotide injection – a treatment that’s rapidly becoming a global sensation in aesthetics. But what exactly are polynucleotides, and why is everyone talking about them?
What Are Polynucleotides?
Polynucleotides are natural biopolymers composed of nucleotides – the building blocks of DNA and RNA. When introduced into the skin through precise injections, these powerful molecules initiate a cascade of cell regeneration, tissue repair, and deep hydration.
Derived typically from purified salmon DNA (highly biocompatible with human skin), polynucleotides work at a cellular level, improving fibroblast activity, increasing collagen and elastin production, and enhancing skin quality from within.
In simpler terms: polynucleotides help your skin repair, regenerate, and glow – naturally.
Derived typically from purified salmon DNA (highly biocompatible with human skin), polynucleotides work at a cellular level, improving fibroblast activity, increasing collagen and elastin production, and enhancing skin quality from within.
In simpler terms: polynucleotides help your skin repair, regenerate, and glow – naturally.

Why Is This Treatment Booming?
The boom in polynucleotide therapy isn’t just hype – it’s backed by real science and clinical results.
What’s So Special About Polynucleotides?
- Stimulate Fibroblasts – Boosts natural collagen and elastin for plumper, firmer skin. ecial About Polynucleotides?
- Anti-inflammatory – Helps calm and repair irritated, acne-prone, or rosacea-prone skin.
- Tissue Healing – Accelerates regeneration after cosmetic procedures or environmental damage.
- Long-term Skin Health – Unlike fillers that fade over time, polynucleotides support true skin remodeling over weeks and months.
- Suitable for All Skin Types – Including mature, dry, sensitive, or even oily skin.

Why Is It Unique Compared to Other Skin Treatments?
| Treatment | Function | Depth of Action | Natural Regeneration |
|---|---|---|---|
| Hyaluronic Acid Fillers | Add volume | Surface/subdermal | ✖️ |
| Botox | Muscle relaxation | Neuromuscular | ✖️ |
| PRP (Platelet-Rich Plasma) | Stimulates growth | Variable | ✔️ |
| Polynucleotides | Rebuild tissue, hydrate, renew | Deep cellular | ✔️✔️✔️ |
This is not a one-size-fits-all treatment, it’s a bespoke regeneration plan, guided by science and executed by experts.
Book a Consultation Today
At Este Hair Medical, our mission is to bring the most innovative, safe, and effective treatments to our clients. Polynucleotide therapy is more than a trend – it’s a scientifically advanced, regenerative solution that’s changing how we treat aging and tired skin.
Whether you're looking to revive dull skin, reduce fine lines, improve texture, or simply boost your skin’s resilience, polynucleotides are a game-changer.




